RRC ID 52823
著者 Hagiwara D, Sakamoto K, Abe K, Gomi K.
タイトル Signaling pathways for stress responses and adaptation in Aspergillus species: stress biology in the post-genomic era.
ジャーナル Biosci Biotechnol Biochem
Abstract Aspergillus species are among the most important filamentous fungi in terms of industrial use and because of their pathogenic or toxin-producing features. The genomes of several Aspergillus species have become publicly available in this decade, and genomic analyses have contributed to an integrated understanding of fungal biology. Stress responses and adaptation mechanisms have been intensively investigated using the accessible genome infrastructure. Mitogen-activated protein kinase (MAPK) cascades have been highlighted as being fundamentally important in fungal adaptation to a wide range of stress conditions. Reverse genetics analyses have uncovered the roles of MAPK pathways in osmotic stress, cell wall stress, development, secondary metabolite production, and conidia stress resistance. This review summarizes the current knowledge on the stress biology of Aspergillus species, illuminating what we have learned from the genomic data in this "post-genomic era."
巻・号 80(9)
ページ 1667-80
公開日 2016-9-1
DOI 10.1080/09168451.2016.1162085
PMID 27007956
MeSH Adaptation, Physiological / genetics* Aspergillus / genetics* Aspergillus / physiology Gene Expression Regulation, Fungal Genome, Fungal Genomics MAP Kinase Signaling System / genetics* Osmotic Pressure / physiology Stress, Physiological / genetics*
IF 1.516
引用数 22
リソース情報
病原微生物