RRC ID 53071
Author Hirooka S, Hirose Y, Kanesaki Y, Higuchi S, Fujiwara T, Onuma R, Era A, Ohbayashi R, Uzuka A, Nozaki H, Yoshikawa H, Miyagishima SY.
Title Acidophilic green algal genome provides insights into adaptation to an acidic environment.
Journal Proc Natl Acad Sci U S A
Abstract Some microalgae are adapted to extremely acidic environments in which toxic metals are present at high levels. However, little is known about how acidophilic algae evolved from their respective neutrophilic ancestors by adapting to particular acidic environments. To gain insights into this issue, we determined the draft genome sequence of the acidophilic green alga Chlamydomonas eustigma and performed comparative genome and transcriptome analyses between Ceustigma and its neutrophilic relative Chlamydomonas reinhardtii The results revealed the following features in Ceustigma that probably contributed to the adaptation to an acidic environment. Genes encoding heat-shock proteins and plasma membrane H+-ATPase are highly expressed in Ceustigma This species has also lost fermentation pathways that acidify the cytosol and has acquired an energy shuttle and buffering system and arsenic detoxification genes through horizontal gene transfer. Moreover, the arsenic detoxification genes have been multiplied in the genome. These features have also been found in other acidophilic green and red algae, suggesting the existence of common mechanisms in the adaptation to acidic environments.
Volume 114(39)
Pages E8304-E8313
Published 2017-9-26
DOI 10.1073/pnas.1707072114
PII 1707072114
PMID 28893987
PMC PMC5625915
MeSH Adaptation, Physiological / genetics* Chlamydomonas reinhardtii / genetics* Chlamydomonas reinhardtii / metabolism Genome, Plant* Hydrogen-Ion Concentration Plant Proteins / genetics* Plant Proteins / metabolism
IF 9.412
Times Cited 22
Algae NIES-2499