論文 - 詳細
| RRC ID | 53686 |
|---|---|
| 著者 | Goren MG, Yosef I, Qimron U. |
| タイトル | Programming Bacteriophages by Swapping Their Specificity Determinants. |
| ジャーナル | Trends Microbiol |
| Abstract |
Bacteriophages, bacteria's natural enemies, may serve as potent antibacterial agents. Their specificity for certain bacterial sub-species limits their effectiveness, but allows selective targeting of bacteria. Lu and colleagues present a platform for such targeting through alteration of bacteriophages' host specificity by swapping specificity domains in their host-recognition ligand. |
| 巻・号 | 23(12) |
| ページ | 744-746 |
| 公開日 | 2015-12-1 |
| DOI | 10.1016/j.tim.2015.10.006 |
| PII | S0966-842X(15)00232-2 |
| PMID | 26526502 |
| MeSH | Bacteria / virology* Bacterial Infections / microbiology* Bacterial Infections / therapy* Bacteriophages / growth & development* Biological Therapy / methods* Complementary Therapies / methods* Humans |
| IF | 13.546 |
| 引用数 | 6 |
| リソース情報 | |
| 原核生物(大腸菌) | |