RRC ID 5370
著者 Yoneyama F, Imura Y, Ichimasa S, Fujita K, Zendo T, Nakayama J, Matsuzaki K, Sonomoto K.
タイトル Lacticin Q, a lactococcal bacteriocin, causes high-level membrane permeability in the absence of specific receptors.
ジャーナル Appl Environ Microbiol
Abstract To characterize the mode of action of lacticin Q (LnqQ), its membrane-permeabilizing activity was compared with that of nisin A because of the similar antimicrobial features of these compounds. Lipid II, the receptor for nisin A, was not required for LnqQ activity. LnqQ induced high-level membrane permeability in the absence of specific receptors.
巻・号 75(2)
ページ 538-41
公開日 2009-1-1
DOI 10.1128/AEM.01827-08
PII AEM.01827-08
PMID 19011053
PMC PMC2620724
MeSH Amino Acid Sequence Anti-Bacterial Agents / pharmacology* Bacteria / drug effects Bacteriocins / chemistry Bacteriocins / pharmacology* Cell Membrane / drug effects* Nisin / pharmacology Permeability / drug effects* Protein Structure, Secondary
IF 4.016
引用数 33
WOS 分野 BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY
リソース情報
一般微生物 JCM2257 JCM5890