RRC ID 53934
Author Noma Y, Sideras P, Naito T, Bergstedt-Lindquist S, Azuma C, Severinson E, Tanabe T, Kinashi T, Matsuda F, Yaoita Y.
Title Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter.
Journal Nature
Abstract Complementary DNA encoding the IgG1 induction factor, the first lymphokine directed to B lymphocytes, from a murine T-cell line has been cloned using a new strategy. The putative primary amino-acid sequence was deduced from the nucleotide sequence determined. The lymphokine synthesized by the direction of this cloned cDNA has many other functions, such as production of B-cell growth factor-1 and induction of Ia on B cells.
Volume 319(6055)
Pages 640-6
Published 1986-2-20
DOI 10.1038/319640a0
PMID 3005865
MeSH Amino Acid Sequence Animals B-Lymphocytes / immunology* Base Sequence Chromosome Mapping Cloning, Molecular DNA / genetics DNA Restriction Enzymes Genetic Vectors Growth Substances / genetics* Histocompatibility Antigens Class II / analysis Immunoglobulin G / biosynthesis Interleukin-4 Lymphokines / genetics* Mice Promoter Regions, Genetic Protein Biosynthesis RNA, Messenger / genetics T-Lymphocytes / physiology* Xenopus laevis
IF 42.779
Times Cited 547
Altmetric score
オルトメトリクス指標項目
The most frequently cited source Patent(IFI CLAIMS)
Total number of mentions 33
Altmetric score changes over past 6months 0.0
Resource
DNA material pSP6K. m. IL-4-374 (RDB01173)