論文 - 詳細
| RRC ID | 54290 |
|---|---|
| 著者 | Sakai T, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Fukumura S, Kobayashi M, Tsutsumi H, Kocsis JD, Honmou O. |
| タイトル | Functional recovery after the systemic administration of mesenchymal stem cells in a rat model of neonatal hypoxia-ischemia. |
| ジャーナル | J Neurosurg Pediatr |
| Abstract |
The authors intravenously infused mesenchymal stem cells (MSCs) into a rat model of neonatal hypoxia-ischemia and found improvements in functional outcome, increased brain volume, and enhanced synaptogenesis. The results of this animal study suggest that the intravenous administration of MSCs should be further explored as a potential treatment for patients suffering from cerebral palsy after hypoxic-ischemic encephalopathy. |
| 巻・号 | 22(5) |
| ページ | 513-522 |
| 公開日 | 2018-11-1 |
| DOI | 10.3171/2018.5.PEDS1845 |
| PII | 2018.5.PEDS1845 |
| PMID | 30074448 |
| MeSH | Animals Brain / physiopathology* Disease Models, Animal Hypoxia-Ischemia, Brain / physiopathology Hypoxia-Ischemia, Brain / therapy* Mesenchymal Stem Cell Transplantation* Rats Rats, Sprague-Dawley Recovery of Function / physiology* |
| IF | 2.162 |
| 引用数 | 1 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ラット | W-Tg(CAG-GFP)184Ys (strainID=525) |