RRC ID 54591
Author Ohtani M, Kawabe H, Demura T.
Title Evidence that thiol-based redox state is critical for xylem vessel cell differentiation.
Journal Plant Signal Behav
Abstract Nitric oxide (NO), which plays essential roles in a variety of cell signaling processes, is the precursor of a family of NO-derived molecules, including toxic reactive nitrogen species. The NO-based regulation of cellular activity is mediated by the reversible modification of cysteine thiol groups in redox-sensitive proteins. One such modification is protein S-nitrosylation, i.e., the addition of an NO moiety to a cysteine thiol, and this S-nitrosylation is regulated by enzymes such as S-nitrosoglutathione reductase (GSNOR). Recently, we reported a novel loss-of-function allele of gsnor1, named suppressor of ectopic vessel cell differentiation induced by VND7-1 (seiv1), based on the VND7-inducible system, in which almost all cell types are transdifferentiated into xylem vessel cells upon activation of the NAC transcription factor VND7. We also found that VND7 can be S-nitrosylated and that the target cysteine residues for S-nitrosylation are critical for VND7 transactivation activity. Here, we further discuss roles for GSNOR1 in xylem vessel cell differentiation, and provide additional data on the effects of cellular NO level on VND7 activity.
Volume 13(4)
Pages e1428512
Published 2018-4-3
DOI 10.1080/15592324.2018.1428512
PMID 29393823
PMC PMC5933917
MeSH Arabidopsis / metabolism* Arabidopsis Proteins / metabolism* Cell Differentiation / physiology Gene Expression Regulation, Plant / physiology Glutathione Reductase / metabolism Nitric Oxide / metabolism Oxidation-Reduction Signal Transduction / physiology Transcription Factors / metabolism Xylem / metabolism*
IF 1.644
Times Cited 4
Arabidopsis / Cultured plant cells, genes rpc00008