論文 - 詳細
| RRC ID | 56239 |
|---|---|
| 著者 | Xiao G, Zhao L, Huang Q, Yang J, Du H, Guo D, Xia M, Li G, Chen Z, Wang D. |
| タイトル | Toxicity evaluation of Wanzhou watershed of Yangtze Three Gorges Reservior in the flood season in Caenorhabditis elegans. |
| ジャーナル | Sci Rep |
| Abstract |
Three Gorges Reservoir (TGR) in the upper stream of Yangtze River in China is a reservoir with the largest and the longest yearly water-level drop. Considering the fact that most of safety assessments of water samples collected from TGR region were based on chemical analysis, we here employed Caenorhabditis elegans to perform in vivo safety assessment of original surface water samples collected from TGR region in the flood season in Wanzhou, Chongqing. Among the examined five original surface water samples, only exposure to original surface water sample collected from backwater area could induce the significant intestinal ROS production, enhance the intestinal permeability, and decrease the locomotion behavior. Additionally, exposure to original surface water sample collected from backwater area altered the expressions of sod-2, sod-5, clk-1, and mev-1. Moreover, mutation of sod-2 or sod-5 was susceptible to the potential toxicity of original surface water sample collected from backwater area on nematodes. Together, our results imply that exposure to surface water sample from the backwater area may at least cause the adverse effects on intestinal function and locomotion behavior in nematodes. |
| 巻・号 | 8(1) |
| ページ | 6734 |
| 公開日 | 2018-4-30 |
| DOI | 10.1038/s41598-018-25048-w |
| PII | 10.1038/s41598-018-25048-w |
| PMID | 29712953 |
| PMC | PMC5928115 |
| MeSH | Animals Caenorhabditis elegans / chemistry Caenorhabditis elegans / drug effects China Environmental Monitoring* Floods / classification* Locomotion / drug effects* Rivers / chemistry Seasons Water Pollutants, Chemical / analysis* |
| IF | 4.011 |
| 引用数 | 10 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 8 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 線虫 | tm1146 |