RRC ID 56265
Author Hara S, Hara Y, Arai MA, Kusuya Y, Takahashi H, Yaguchi T, Ishibashi M.
Title Isolation of Nabscessin C from Nocardia abscessus IFM 10029T and a Study on Biosynthetic Pathway for Nabscessins.
Journal Chem Pharm Bull (Tokyo)
Abstract A new aminocyclitol derivative, designated nabscessin C (1), was isolated from Nocardia abscessus IFM 10029T. Nabcessin C is an isomer of nabscessins A (2) and B (3) with different positioning of the acyl group. Absolute configuration of nabscessin A was determined by conversion into the 2-deoxy-scyllo-inosamine pentaacetyl derivative (4) by hydrolysis and acetylation of 2. The biosynthetic pathway of nabscessins is proposed based on gene expression analysis.
Volume 66(10)
Pages 976-982
Published 2018-1-1
DOI 10.1248/cpb.c18-00430
PMID 30270243
MeSH Acetylation Animals Cell Line Cell Proliferation Cyclitols / chemistry Cyclitols / isolation & purification Cyclitols / metabolism* Hydrolysis Mice Molecular Structure Nocardia asteroides / chemistry* Nocardia asteroides / metabolism Seeds / chemistry Seeds / metabolism
IF 1.405
Times Cited 1
Resource
Pathogenic eukaryotic microorganisms 病原放線菌: IFM 10029