| RRC ID |
56267
|
| Author |
Hirose M, Noguchi H, Yaguchi T, Matsumoto T, Hiruma M, Fukushima S, Ihn H.
|
| Title |
Onychomycosis caused by Aspergillus subramanianii.
|
| Journal |
J Dermatol
|
| Abstract |
We describe a case of a 23-year-old female patient with no apparent underlying diseases. She showed a discoloration of the proximal portion of the left big toenail with paronychia. Direct microscopy revealed septate hyphae with conidiophores, and a periodic acid-Schiff-stained nail specimen revealed septate hyphae branching at angles of approximately 45°. On the basis of phylogenetic analysis, we finally arrived at the diagnosis of ungual aspergillosis caused by Aspergillus subramanianii. After p.o. administration of terbinafine and topical application of 10% efinaconazole solution, the disease resolved in 6 months. A. subramanianii is one of the new species in the genus Aspergillus section Circumdati. Reported clinical isolates have been isolated from lung tissue, wounds and feet. This is the first documented case of onychomycosis caused by A. subramanianii. Onychomycosis due to Aspergillus species is uncommon. We summarized the reported cases of ungual aspergillosis in Japan.
|
| Volume |
45(11)
|
| Pages |
1362-1366
|
| Published |
2018-11-1
|
| DOI |
10.1111/1346-8138.14616
|
| PMID |
30144137
|
| MeSH |
Administration, Cutaneous
Administration, Oral
Adult
Antifungal Agents / therapeutic use*
Aspergillosis / diagnostic imaging
Aspergillosis / drug therapy
Aspergillosis / microbiology*
Aspergillosis / pathology
Aspergillus / isolation & purification
Aspergillus / pathogenicity*
Female
Foot Dermatoses / diagnostic imaging
Foot Dermatoses / drug therapy
Foot Dermatoses / microbiology*
Foot Dermatoses / pathology
Humans
Hyphae / isolation & purification
Japan
Microscopy
Onychomycosis / diagnostic imaging
Onychomycosis / drug therapy
Onychomycosis / microbiology*
Onychomycosis / pathology
Terbinafine / therapeutic use
Triazoles / therapeutic use
Young Adult
|
| IF |
3.377
|
| Times Cited |
2
|
| Resource |
| Pathogenic eukaryotic microorganisms |
病原真菌：IFM 64492 |
