RRC ID 56336
著者 Murata M, Ishii A, Fujimoto H, Nishimura K, Kosaka T, Mori H, Yamada M.
タイトル Update of thermotolerant genes essential for survival at a critical high temperature in Escherichia coli.
ジャーナル PLoS One
Abstract Previous screening of a single-gene knockout library consisting of 3,908 disrupted-mutant strains allowed us to identify 51 thermotolerant genes that are essential for survival at a critical high temperature (CHT) in Escherichia coli [Murata M, Fujimoto H, Nishimura K, Charoensuk K, Nagamitsu H, Raina S, Kosaka T, Oshima T, Ogasawara N, Yamada M (2011) PLoS ONE 6: e20063]. In this study, we identified another 21 thermotolerant genes. E. coli thus has 72 thermotolerant genes in total. The genes are classified into 8 groups: genes for energy metabolism, outer membrane organization, DNA double-strand break repair, tRNA modification, protein quality control, translation control, cell division and transporters. This classification and physiological analysis indicate the existence of fundamental strategies for survival at a CHT, which seems to exclude most of the heat shock responses.
巻・号 13(2)
ページ e0189487
公開日 2018-2-27
DOI 10.1371/journal.pone.0189487
PII PONE-D-17-20327
PMID 29485997
PMC PMC5828445
MeSH Adaptation, Physiological* Escherichia coli / genetics* Escherichia coli / physiology* Genes, Bacterial* Genetic Complementation Test Hot Temperature*
IF 2.74
引用数 5
リソース情報
原核生物(大腸菌) Keio collection