| RRC ID |
56791
|
| Author |
Takayuki Hoshino, Moto Yoshioka, Akira Wagatsuma, Hiroki Miyazako, Kunihiko Mabuchi
|
| Title |
Fine virtual cathode display for biomolecules control and cell nano surgery
|
| Journal |
2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS)
|
| Abstract |
Electron beam (EB) induced fine virtual cathode (VC) on a 100-nm-thick SiN membrane has been developed using inverted-EB lithography (I-EBL). Here we present electrokinetic property of the VC for biological materials and instantly control their spatio-temporal responses using the VC. Negatively charged biomolecules (proteins, DNAs) respond to locally injected negative electrons of VC, and change their electrostatic interaction which affects the molecular aggregation/dissociation and adhesion/detachment in water solution. So, we call this technique virtual cathode display for biomolecules. This technique was applied to in-situ molecules patterning for mechanical strain microscopy and pinpoint transmembrane molecules delivery.
|
| Published |
2017-1-1
|
| DOI |
10.1109/MEMSYS.2017.7863471
|
| Resource |
| Human and Animal Cells |
C2C12(RCB0987) |
