論文 - 詳細
| RRC ID | 56864 |
|---|---|
| 著者 | Kubota T, Nakamura K, Kurimoto SI, Sakai K, Fromont J, Gonoi T, Kobayashi J. |
| タイトル | Zamamidine D, a Manzamine Alkaloid from an Okinawan Amphimedon sp. Marine Sponge. |
| ジャーナル | J Nat Prod |
| Abstract |
A new manzamine alkaloid, zamamidine D (1), was isolated from an Okinawan Amphimedon sp. marine sponge. The structure of zamamidine D (1) including the relative configuration was elucidated on the basis of spectroscopic data. Zamamidine D (1) is the first manzamine alkaloid possessing a 2,2'-methylenebistryptamine unit as the aromatic moiety instead of a β-carboline unit. Zamamidine D (1) showed antimicrobial activity against several bacteria and fungi. |
| 巻・号 | 80(4) |
| ページ | 1196-1199 |
| 公開日 | 2017-4-28 |
| DOI | 10.1021/acs.jnatprod.6b01110 |
| PMID | 28207259 |
| MeSH | Alkaloids / chemistry Alkaloids / isolation & purification* Alkaloids / pharmacology Animals Carbazoles / chemistry Carbolines / chemistry Carbolines / isolation & purification* Carbolines / pharmacology Drug Screening Assays, Antitumor Japan Marine Biology Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Porifera / chemistry* |
| IF | 3.885 |
| 引用数 | 10 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
|
| 最多言及媒体 | News |
| 各媒体での言及数の合計 | 3 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 病原真核微生物 | 病原真菌：IFM 62678, IFM 62679, IFM 62680, IFM 62681, IFM 2066 |