論文 - 詳細
| RRC ID | 56865 |
|---|---|
| 著者 | Hara S, Ishikawa N, Hara Y, Nehira T, Sakai K, Gonoi T, Ishibashi M. |
| タイトル | Nabscessins A and B, Aminocyclitol Derivatives from Nocardia abscessus IFM 10029T. |
| ジャーナル | J Nat Prod |
| Abstract |
Two new aminocyclitol amide derivatives, nabscessins A (1) and B (2), were isolated from the culture broth of a pathogenic actinomycete species, Nocardia abscessus IFM 10029T. The structures of nabscessins A and B were elucidated by spectral studies, and the compounds showed antifungal activity against Cryptococcus neoformans, with IC50 values of 32 and 16 μg/mL, respectively. |
| 巻・号 | 80(2) |
| ページ | 565-568 |
| 公開日 | 2017-2-24 |
| DOI | 10.1021/acs.jnatprod.6b00935 |
| PMID | 28112922 |
| MeSH | Actinobacteria / chemistry Antifungal Agents / chemistry Antifungal Agents / isolation & purification* Antifungal Agents / pharmacology* Cryptococcus neoformans / drug effects Cyclitols / chemistry Cyclitols / isolation & purification* Microbial Sensitivity Tests Molecular Structure Nocardia / chemistry* Phylogeny RNA, Ribosomal, 16S / chemistry |
| IF | 3.885 |
| 引用数 | 12 |
| リソース情報 | |
| 病原真核微生物 | 病原放線菌：IFM 10029 |