Reference - Detail
| RRC ID | 56874 |
|---|---|
| Author | Ikegami K, Yoshimura T. |
| Title | Circadian clocks and the measurement of daylength in seasonal reproduction. |
| Journal | Mol Cell Endocrinol |
| Abstract |
Temperate zone organisms measure changes in daylength to adapt to seasonal changes in their environment. Recent studies have revealed that the long day (LD)-induced thyrotropin (TSH) in the pars tuberalis (PT) of the pituitary gland act as a master factor regulating seasonal reproduction on the the ependymal cells (ECs) within the mediobasal hypothalamus (MBH) to induce expression of type 2 deiodinase (Dio2), a thyroid hormone (TH)-activating enzyme in both LD and short day (SD) breeders. Locally activated TH in the MBH is believed to trigger GnRH secretion from the hypothalamus in LD breeders, while it terminates reproductive activity in SD breeders. Circadian clock is involved in seasonal time measurement and clock genes are expressed in the PT and ECs. Although circadian and melatonin-dependent control of TSH appears to link the circadian clock and the photoperiodic response in mammals, how this circadian clock measure daylength remains to be clarified. |
| Volume | 349(1) |
| Pages | 76-81 |
| Published | 2012-2-5 |
| DOI | 10.1016/j.mce.2011.06.040 |
| PII | S0303-7207(11)00373-X |
| PMID | 21767603 |
| MeSH | Animals Circadian Clocks* Circadian Rhythm Melatonin / metabolism Photoperiod* Reproduction* Seasons* Suprachiasmatic Nucleus / metabolism Suprachiasmatic Nucleus / physiology Thyroid Hormones / metabolism Thyrotropin / metabolism |
| IF | 3.693 |
| Times Cited | 39 |
| Altmetric score |
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Chicken / Quail | |