RRC ID 57019
著者 Ryuno H, Nigo F, Naguro I, Sekimizu K, Kaito C.
タイトル Staphylococcus aureus aggregation in the plasma fraction of silkworm hemolymph.
ジャーナル PLoS One
Abstract Staphylococcus aureus formed bacterial aggregates in the plasma fraction of the hemolymph of silkworm, the larva of Bombyx mori, in a growth-dependent manner. The addition of arabinose or galactose inhibited the formation of S. aureus aggregates in the silkworm plasma. Formation of the bacterial aggregates depended on S. aureus genes required for the synthesis of bacterial surface polysaccharides-ypfP and ltaA, which are involved in lipoteichoic acid synthesis, and the tagO gene, which is involved in wall teichoic acid synthesis. These findings suggest that S. aureus forms bacterial aggregates in the silkworm plasma via bacterial surface teichoic acids.
巻・号 14(5)
ページ e0217517
公開日 2019-1-1
DOI 10.1371/journal.pone.0217517
PII PONE-D-19-04179
PMID 31145754
PMC PMC6542516
MeSH Animals Arabinose / pharmacology Bombyx / genetics* Bombyx / metabolism Bombyx / microbiology Cell Aggregation / drug effects* Cell Aggregation / genetics Galactose / pharmacology Glycosyltransferases / genetics Hemolymph / metabolism Hemolymph / microbiology Insect Proteins / genetics Insect Proteins / metabolism Larva / genetics Larva / metabolism Lipopolysaccharides / biosynthesis Lipopolysaccharides / genetics Lipopolysaccharides / metabolism Staphylococcal Infections / drug therapy Staphylococcal Infections / metabolism Staphylococcal Infections / microbiology* Staphylococcus aureus / drug effects* Staphylococcus aureus / genetics Staphylococcus aureus / pathogenicity Teichoic Acids / biosynthesis
IF 2.776
引用数 0
リソース情報
カイコ