| RRC ID |
57310
|
| Author |
Tomita S, Sue M, Kajikawa A, Igimi S, Shinohara H, Yokota K.
|
| Title |
Detoxification process of tolaasins, lipodepsipeptides, by Microbacterium sp. K3-5.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
Tolaasins are antimicrobial lipodepsipeptides. Here, we report the tolaasins-detoxifying properties of Microbacterium sp. K3-5 (K3-5). The detoxification of tolaasins by K3-5 was performed by hydrolyzation of cyclic structure of tolaasins depending on the tolaasin-K3-5 cell interaction. Our data suggest that the cyclic structure of tolaasins is critical for its interaction to target cells.
|
| Volume |
82(8)
|
| Pages |
1455-1458
|
| Published |
2018-8-1
|
| DOI |
10.1080/09168451.2018.1460575
|
| PMID |
29658402
|
| MeSH |
Actinobacteria / metabolism*
Chromatography, Liquid
Depsipeptides / chemistry
Depsipeptides / metabolism*
Inactivation, Metabolic*
Lipopeptides / chemistry
Lipopeptides / metabolism*
Peptides, Cyclic / chemistry
Peptides, Cyclic / metabolism
Protein Conformation
Spectrometry, Mass, Electrospray Ionization
|
| IF |
1.297
|
| Times Cited |
1
|
| Resource |
| General Microbes |
JCM 1465 |
