RRC ID |
57514
|
Author |
Kitou Y, Nakajima Y, Maeda K, Jin Q, Nishiuchi T, Kanamaru K, Kobayashi T, Kimura M.
|
Title |
Re-examination of genetic and nutritional factors related to trichothecene biosynthesis in Fusarium graminearum.
|
Journal |
Biosci Biotechnol Biochem
|
Abstract |
Disruption of two Fusarium genes that negatively regulate trichothecene biosynthesis was reported to cause a drastic increase in trichothecene production. However, careful inspection of these genes revealed that neither was significantly related to trichothecene production. Agmatine medium maintained the expression of trichothecene genes at significant levels, resulting in a 2-3-fold increase in the final yield, as compared to glutamine medium.
|
Volume |
80(2)
|
Pages |
414-7
|
Published |
2016-1-1
|
DOI |
10.1080/09168451.2015.1088374
|
PMID |
26413981
|
MeSH |
Agmatine / metabolism
Agmatine / pharmacology
Culture Media / pharmacology
Fungal Proteins / genetics*
Fungal Proteins / metabolism
Fusarium / drug effects
Fusarium / genetics*
Fusarium / metabolism
Gene Deletion
Gene Expression Regulation, Fungal*
Glutamine / metabolism
Glutamine / pharmacology
Transcription Factors / genetics*
Transcription Factors / metabolism
Transcription, Genetic
Trichothecenes / biosynthesis*
Trichothecenes / genetics
|
IF |
1.297
|
Times Cited |
1
|
Resource |
General Microbes |
JCM 9873 |