| RRC ID |
57515
|
| Author |
Takagaki A, Nanjo F.
|
| Title |
Biotransformation of (-)-epicatechin, (+)-epicatechin, (-)-catechin, and (+)-catechin by intestinal bacteria involved in isoflavone metabolism.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
Isoflavone-metabolizing bacteria, Adlercreutzia equolifaciens, Asaccharobacter celatus, Slackia equolifaciens, and Slackia isoflavoniconvertens catalyzed C-ring cleavage of (-)-epicatechin and (+)-catechin, (+)-epicatechin, and (-)-catechin in varying degrees. The cleaving abilities of (-)-epicatechin and (+)-catechin were enhanced by hydrogen, except (+)-catechin cleavage by S. equolifaciens, which was not accelerated. (-)-Catechin cleavage by Ad. equolifaciens was remarkably accelerated by hydrogen.
|
| Volume |
80(1)
|
| Pages |
199-202
|
| Published |
2016-1-1
|
| DOI |
10.1080/09168451.2015.1079480
|
| PMID |
26312950
|
| MeSH |
Actinobacteria / drug effects
Actinobacteria / metabolism*
Biotransformation
Catechin / metabolism*
Hydrogen / pharmacology
Stereoisomerism
|
| IF |
1.297
|
| Times Cited |
9
|
| Resource |
| General Microbes |
JCM 14793, JCM 14811, JCM 16059, JCM 16137 |
