RRC ID 584
Author Romano PG, Horton P, Gray JE.
Title The Arabidopsis cyclophilin gene family.
Journal Plant Physiol.
Abstract Database searching has allowed the identification of a number of previously unreported single and multidomain isoform members of the Arabidopsis cyclophilin gene family. In addition to the cyclophilin-like peptidyl-prolyl cis-trans isomerase domain, the latter contain a variety of other domains with characterized functions. Transcriptional analysis showed they are expressed throughout the plant, and different isoforms are present in all parts of the cell including the cytosol, nucleus, mitochondria, secretory pathway, and chloroplast. The abundance and diversity of cyclophilin isoforms suggests that, like their animal counterparts, plant cyclophilins are likely to be important proteins involved in a wide variety of cellular processes. As well as fulfilling the basic role of protein folding, they may also play important roles in mRNA processing, protein degradation, and signal transduction and thus may be crucial during both development and stress responsiveness.
Volume 134(4)
Pages 1268-82
Published 2004-4
DOI 10.1104/pp.103.022160
PII pp.103.022160
PMID 15051864
PMC PMC419803
MeSH Amino Acid Sequence Arabidopsis / enzymology Arabidopsis / genetics* Arabidopsis Proteins / genetics* Arabidopsis Proteins / metabolism Cyclophilin A / chemistry Cyclophilin A / genetics Cyclophilin A / metabolism Cyclophilins / genetics* Cyclophilins / metabolism Gene Expression Regulation, Enzymologic Gene Expression Regulation, Plant Molecular Sequence Data Multigene Family Photosynthetic Reaction Center Complex Proteins / genetics* Photosynthetic Reaction Center Complex Proteins / metabolism Phylogeny Sequence Homology, Amino Acid
IF 6.305
Times Cited 134
Arabidopsis / Cultured plant cells, genes pda02459 pda02396 pda04293 pda03027 pda02423 pda02588