Reference - Detail
| RRC ID | 58541 |
|---|---|
| Author | Jiang Y, Liu Y, Zhang J. |
| Title | Antibiotic contaminants reduced the treatment efficiency of UV-C on Microcystis aeruginosa through hormesis. |
| Journal | Environ Pollut |
| Abstract |
Antibiotic contaminants exert stimulatory hormetic effects in cyanobacteria at low (ng L-1) concentrations, which may interfere with the control of cyanobacterial bloom in aquatic environments exhibiting combined pollution. This study investigated the influence of a mixture of four popular antibiotics (sulfamethoxazole, amoxicillin, ciprofloxacin, and tetracycline) during the application of UV-C irradiation for controlling the bloom of Microcystis aeruginosa. In the absence of antibiotics, 100-500 mJ cm-2 UV-C irradiation reduced cell density, growth rate, chlorophyll a content, Fv/Fm value and microcystin concentration in M. aeruginosa in a dose-dependent manner through the downregulation of proteins related to cell division, chlorophyll synthesis, photosynthesis and microcystin synthesis. UV-C irradiation stimulated microcystin release through the upregulation of the microcystin release regulatory protein (mcyH). The presence of 40 ng L-1 antibiotic mixture during UV-C treatment significantly reduced (p < 0.05) the treatment efficiency of 100-300 mJ cm-2 UV-C on microcystin concentration, while 80 and 160 ng L-1 antibiotic mixture significantly reduced (p < 0.05) the treatment efficiency of 100-500 mJ cm-2 UV-C on cell density and microcystin concentration. The antibiotic mixture alleviated the toxicity of UV-C on M. aeruginosa through a significant stimulation of photosynthetic activity (p < 0.05) and the upregulation of proteins involved in photosynthesis, biosynthesis, protein expression, and DNA repair. Microcystin release in UV-C-treated cyanobacterial cells was further stimulated by the antibiotic mixture through the upregulation of mcyH and four ATP-binding cassette transport proteins. The interference effects of antibiotic contaminants should be fully considered when UV-C is applied to control cyanobacterial bloom in antibiotic-polluted environments. In order to eliminate the interference effects of antibiotics, the concentration of each target antibiotic is suggested to be controlled below 5 ng L-1 before the application of UV-C irradiation. |
| Volume | 261 |
| Pages | 114193 |
| Published | 2020-6-1 |
| DOI | 10.1016/j.envpol.2020.114193 |
| PII | S0269-7491(19)35347-3 |
| PMID | 32088440 |
| MeSH | Anti-Bacterial Agents* / pharmacology Chlorophyll A / metabolism Hormesis* Microcystins / metabolism Microcystis* / drug effects Microcystis* / radiation effects Ultraviolet Rays* Water Pollutants, Chemical / pharmacology |
| IF | 6.793 |
| Times Cited | 0 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Algae | NIES-843 |