RRC ID 59017
著者 Matsumoto Y, Takahashi M, Umehara M, Asano M, Maruki-Uchida H, Morita M, Sekimizu K.
タイトル Suppressive effects of whey protein hydrolysate on sucrose-induced hyperglycemia in silkworms.
ジャーナル Drug Discov Ther
Abstract Silkworms are useful for evaluating substances that suppress postprandial hyperglycemia by oral administration. In this study, orally administered whey protein hydrolysate (WPH), obtained by enzymatic treatment of whey protein, suppressed sucrose-induced hyperglycemia in silkworms in a dose-dependent manner. WPH also inhibited glucose-induced hyperglycemia in silkworms. These findings suggest that WPH contains a bioactive peptide that inhibits glucose uptake from the intestinal tract and thereby suppresses sucrose-induced hyperglycemia.
巻・号 13(5)
ページ 244-247
公開日 2019-11-14
DOI 10.5582/ddt.2019.01069
PMID 31611487
MeSH Animals Bombyx Dose-Response Relationship, Drug Glucose Hyperglycemia / chemically induced Hyperglycemia / prevention & control* Protein Hydrolysates / pharmacology* Sucrose Whey Proteins / pharmacology*
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