Reference - Detail
| RRC ID | 5910 |
|---|---|
| Author | Kulakovskaya TV, Golubev WI, Tomashevskaya MA, Kulakovskaya EV, Shashkov AS, Grachev AA, Chizhov AS, Nifantiev NE. |
| Title | Production of antifungal cellobiose lipids by Trichosporon porosum. |
| Journal | Mycopathologia |
| Abstract |
The yeast Trichosporon porosum suppresses growth of ascomycetes and basidiomycetes belonging to 52 genera. It is due to secretion of a thermostable fungicidal agent. The suppression was maximal at pH 3.5-4.0. Fungicidal preparation obtained from the culture broth was shown to be a mixture of cellobiosides of dihydrodecane acid with different degree of acetylation of cellobiose residue. The preparation caused the death of Candida albicans and Filobasidiella neoformans cells in the concentrations of 0.2 and 0.03 mM, respectively. |
| Volume | 169(2) |
| Pages | 117-23 |
| Published | 2010-2-1 |
| DOI | 10.1007/s11046-009-9236-2 |
| PMID | 19757153 |
| MeSH | Antifungal Agents / chemistry Antifungal Agents / isolation & purification Antifungal Agents / metabolism* Antifungal Agents / pharmacology* Basidiomycota / drug effects Candida albicans / drug effects Cellobiose / chemistry Cellobiose / isolation & purification Cellobiose / metabolism* Cellobiose / pharmacology* Lipid Metabolism* Lipids / chemistry Lipids / isolation & purification Lipids / pharmacology* Magnetic Resonance Spectroscopy Microbial Viability Molecular Structure Trichosporon / metabolism* |
| IF | 2.452 |
| Times Cited | 22 |
| WOS Category | MYCOLOGY |
| Resource | |
| General Microbes | JCM 1542 |