| RRC ID |
60285
|
| Author |
Sugimura T, Jounai K, Ohshio K, Fujiwara D.
|
| Title |
Plasmacytoid dendritic cell dysfunction caused by heat stress is improved by administration of Lactococcus lactis strain plasma in mice.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
Plasmacytoid dendritic cells (pDCs) are crucial in anti-viral immunity, acting as regulators in both adaptive and innate immunity. In this study, brief heat stress caused a decrease in splenic pDC activity in mice. Administration of Lactococcus lactis strain Plasma (LC-Plasma) significantly suppressed the decrease in pDC activity and IFN-α production. Abbreviations: LC-Plasma: Lactococcus lactis strain Plasma; LAB: lactic acid bacteria; pDC: plasmacytoid dendritic cell; IFN: interferons; mDC: myeloid dendritic cells.
|
| Volume |
83(11)
|
| Pages |
2140-2143
|
| Published |
2019-11-1
|
| DOI |
10.1080/09168451.2019.1642098
|
| PMID |
31318317
|
| MeSH |
Animals
Dendritic Cells / immunology*
Heat-Shock Response / immunology*
Lactococcus lactis / physiology*
Mice
|
| IF |
1.297
|
| Times Cited |
0
|
| Resource |
| General Microbes |
JCM5805 |