| RRC ID |
60291
|
| 著者 |
Kim JH, Lee JM, Jang WJ, Park HD, Kim YO, Kim CH, Kong IS.
|
| タイトル |
Efficient production of poly γ-d-glutamic acid from the bloom-forming green macroalgae, Ulva sp., by Bacillus sp. SJ-10.
|
| ジャーナル |
Biotechnol Bioeng
|
| Abstract |
Numerous studies on poly γ-d-glutamicacid (γ-PGA) production have investigated terrestrial renewable sources for reducing production costs, but there are no studies using waste marine resources so far. We aimed to develop a cost-effective production method of γ-d-PGA by Bacillus sp. SJ-10 using green macroalgae (Ulva sp.) as a major substrate without hydrolysis pretreatment. The SJ-10 was shown to not only cause immediate tissue degradation of the Ulva membrane but also grew well as a sole substrate. The γ-d-PGA yield was 6.29 ± 0.34 g/L under optimized conditions via the response surface method, and the produced γ-d-PGA had a thermal decomposition temperature of 310°C and molecular weight of 250-1780 kDa. The calculated cost efficiency for the final yield was 32% when compared with complex media. Therefore, the present study provided a strategy for promoting an ecofriendly and cost-effective means to produce γ-d-PGA via a marine renewable resource.
|
| 巻・号 |
116(7)
|
| ページ |
1594-1603
|
| 公開日 |
2019-7-1
|
| DOI |
10.1002/bit.26966
|
| PMID |
30883680
|
| MeSH |
Microalgae / growth & development*
Polyglutamic Acid* / biosynthesis
Polyglutamic Acid* / chemistry
Polyglutamic Acid* / isolation & purification
Ulva / growth & development*
|
| IF |
4.26
|
| 引用数 |
2
|
| リソース情報 |
| 一般微生物 |
JCM15709 |
