論文 - 詳細
| RRC ID | 60349 |
|---|---|
| 著者 | Mohapatra B, Kazy SK, Sar P. |
| タイトル | Comparative genome analysis of arsenic reducing, hydrocarbon metabolizing groundwater bacterium Achromobacter sp. KAs 3-5T explains its competitive edge for survival in aquifer environment. |
| ジャーナル | Genomics |
| Abstract |
Whole genome sequence of arsenic (As) reducing, hydrocarbon metabolizing groundwater bacterium Achromobacter sp. KAs 3-5T was explored to understand the genomic basis of its As-ecophysiology and niche adaptation in aquifer environment. The genome (5.6 Mbp, 65.5 G + C mol %) encodes 4840 proteins, 1138 enzymes, 53 tRNAs, 11 rRNAs, 608 signal peptides, and 1.13% horizontally transferred genes. Presence of genes encoding cytosolic As5+-reduction (arsRCBH, ACR3), aromatics utilization (bph, naph, catABC, boxABCD, genACB), Fe-transformation (tonB, achromobactin, FUR, FeR), and denitrification (nar, nap) processes were observed and validated through proteomics. Phylogenomic analysis (< 90% ANI, < 50% DDH) confirmed strain KAs 3-5T to be a novel representative of the genus Achromobacter. An asymptotic open pan-genome (20,855 genes) and high correlation between genomic and ecological diversity suggested niche preference ability of this genus. Assemblage of species specific genes affiliated to transcription-regulation, membrane transport, and redox-transformation explained the strain's competitive survival strategies in As-rich oligotrophic groundwater. |
| 巻・号 | 111(6) |
| ページ | 1604-1619 |
| 公開日 | 2019-12-1 |
| DOI | 10.1016/j.ygeno.2018.11.004 |
| PII | S0888-7543(18)30421-X |
| PMID | 30445215 |
| MeSH | Achromobacter* / genetics Achromobacter* / metabolism Arsenic / metabolism* Genome, Bacterial* Groundwater / microbiology* Hydrocarbons / metabolism* Oxidation-Reduction Water Microbiology* |
| IF | 3.16 |
| 引用数 | 2 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 2 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 一般微生物 | JCM31426 |