RRC ID 60619
著者 Shiratori T, Suzuki S, Kakizawa Y, Ishida KI.
タイトル Phagocytosis-like cell engulfment by a planctomycete bacterium.
ジャーナル Nat Commun
Abstract Phagocytosis is a key eukaryotic feature, conserved from unicellular protists to animals, that enabled eukaryotes to feed on other organisms. It could also be a driving force behind endosymbiosis, a process by which α-proteobacteria and cyanobacteria evolved into mitochondria and plastids, respectively. Here we describe a planctomycete bacterium, 'Candidatus Uab amorphum', which is able to engulf other bacteria and small eukaryotic cells through a phagocytosis-like mechanism. Observations via light and electron microscopy suggest that this bacterium digests prey cells in specific compartments. With the possible exception of a gene encoding an actin-like protein, analysis of the 'Ca. Uab amorphum' genomic sequence does not reveal any genes homologous to eukaryotic phagocytosis genes, suggesting that cell engulfment in this microorganism is probably not homologous to eukaryotic phagocytosis. The discovery of this "phagotrophic" bacterium expands our understanding of the cellular complexity of prokaryotes, and may be relevant to the origin of eukaryotic cells.
巻・号 10(1)
ページ 5529
公開日 2019-12-11
DOI 10.1038/s41467-019-13499-2
PII 10.1038/s41467-019-13499-2
PMID 31827088
PMC PMC6906331
MeSH Alphaproteobacteria / classification Alphaproteobacteria / genetics Alphaproteobacteria / physiology* Alphaproteobacteria / ultrastructure Bacterial Proteins / genetics Bacterial Proteins / metabolism Biological Evolution Genome, Bacterial Phagocytosis* Phylogeny
IF 12.121
引用数 7
リソース情報
一般微生物 JCM39082 JCM1439 JCM1097 JCM6074