RRC ID 60838
著者 Iwahashi C, Eguchi H, Hotta F, Uezumi M, Sawa M, Kimura M, Yaguchi T, Kusaka S.
タイトル Orbital abscess caused by Exophiala dermatitidis following posterior subtenon injection of triamcinolone acetonide: a case report and a review of literature related to Exophiala eye infections.
ジャーナル BMC Infect Dis
Abstract BACKGROUND:Subtenon injection of triamcinolone acetonide (STTA) has been widely adopted in the clinical setting of ophthalmology and its infectious complications are rare. However, orbital abscess following STTA has been reported in seven cases. Furthermore, although eye infections due to Exophiala species are uncommon, there have been 19 cases to date. E. jeanselmei, E. phaeomuriformis, E. werneckii, and E. dermatitidis have been reported to cause human eye infections; however, to the best of our knowledge, orbital abscess caused by E. dermatitidis has not yet been reported. We describe the first documented case of fungal orbital abscess caused by E. dermatitidis following STTA. We also review the related literature of orbital abscess following STTA, as well as eye infections caused by the four Exophiala species.
CASE PRESENTATION:The patient was a 69-year-old Japanese woman with diabetic mellitus. She had a macular oedema in her right eye, which occurred secondary to branch retinal vein occlusion. An orbital abscess caused by E. dermatitidis occurred 4 months after the second STTA for the macular oedema, which was successfully treated by a surgical debridement and systemic administration of voriconazole.
CONCLUSIONS:Our findings in the patient and from our literature survey caution ophthalmologists to the fact that STTA can cause fungal orbital infections, especially in diabetic patients. Furthermore, surgical treatment is one of the most important risk factors.
巻・号 20(1)
ページ 566
公開日 2020-8-3
DOI 10.1186/s12879-020-05294-y
PII 10.1186/s12879-020-05294-y
PMID 32746887
PMC PMC7398408
MeSH Abscess / microbiology Aged Anti-Inflammatory Agents / adverse effects* Anti-Inflammatory Agents / therapeutic use Antifungal Agents / therapeutic use Dermatitis / diagnosis* Dermatitis / drug therapy Dermatitis / microbiology Exophiala / isolation & purification* Eye Infections / diagnosis* Eye Infections / drug therapy Eye Infections / microbiology Female Humans Macular Edema / diagnosis Macular Edema / etiology Triamcinolone Acetonide / adverse effects* Triamcinolone Acetonide / therapeutic use Voriconazole / therapeutic use
IF 2.565
引用数 0
リソース情報
病原真核微生物 Exophiala dermatitidis IFM 65961