Reference - Detail
| RRC ID | 610 |
|---|---|
| Author | Yan Y, Kohli A, Koffas MA. |
| Title | Biosynthesis of natural flavanones in Saccharomyces cerevisiae. |
| Journal | Appl Environ Microbiol |
| Abstract |
A four-step flavanone biosynthetic pathway was constructed and introduced into Saccharomyces cerevisiae. The recombinant yeast strain was fed with phenylpropanoid acids and produced the flavanones naringenin and pinocembrin 62 and 22 times more efficiently compared to previously reported recombinant prokaryotic strains. Microbial biosynthesis of the flavanone eriodictyol was also achieved. |
| Volume | 71(9) |
| Pages | 5610-3 |
| Published | 2005-9-1 |
| DOI | 10.1128/AEM.71.9.5610-5613.2005 |
| PII | 71/9/5610 |
| PMID | 16151160 |
| PMC | PMC1214632 |
| MeSH | Flavanones / biosynthesis* Industrial Microbiology / methods Multigene Family* Phenylpropionates / metabolism Plant Proteins / genetics* Plant Proteins / metabolism Recombinant Proteins / genetics Recombinant Proteins / metabolism* Saccharomyces cerevisiae / genetics Saccharomyces cerevisiae / growth & development Saccharomyces cerevisiae / metabolism* |
| IF | 4.016 |
| Times Cited | 133 |
| WOS Category | BIOTECHNOLOGY & APPLIED MICROBIOLOGY MICROBIOLOGY |
| Resource | |
| Arabidopsis / Cultured plant cells, genes | pda03082 |