論文 - 詳細
| RRC ID | 61200 |
|---|---|
| 著者 | Puilingi CG, Kudo Y, Cho Y, Konoki K, Yotsu-Yamashita M. |
| タイトル | A new sarasinoside congener, sarasinoside M2, from a marine sponge collected in the Solomon Islands. |
| ジャーナル | Biosci Biotechnol Biochem |
| Abstract |
A new sarasinoside congener (sarasinoside M2) and known sarasinoside B1 were obtained from a marine sponge. Sarasinoside M2 was suggested to have the same aglycon as sarasinoside M although the internal glucose in its sugar moiety is replaced by xylose. Sarasinosides B1 and M2 showed moderate cytotoxicity (approximate IC50 5-18 μM) toward Neuro-2a and HepG2 cell lines. |
| 巻・号 | 81(2) |
| ページ | 222-225 |
| 公開日 | 2017-2-1 |
| DOI | 10.1080/09168451.2016.1246172 |
| PMID | 27760495 |
| MeSH | Animals Antineoplastic Agents / chemistry Antineoplastic Agents / isolation & purification* Antineoplastic Agents / pharmacology* Glycosides / chemistry Glycosides / isolation & purification* Glycosides / pharmacology* Hep G2 Cells Humans Inhibitory Concentration 50 Melanesia Mice Porifera / chemistry* |
| IF | 1.516 |
| リソース情報 | |
| ヒト・動物細胞 | NB2a(RCB2639) Hep G2(RCB1886) |