| RRC ID |
61404
|
| Author |
Umezawa T, Chen P, Tsutsumi Y, Doi H, Ashida M, Suzuki S, Moriyama K, Hanawa T.
|
| Title |
Calcification of MC3T3-E1 cells on titanium and zirconium.
|
| Journal |
Dent Mater J
|
| Abstract |
To confirm similarity of hard tissue compatibility between titanium and zirconium, calcification of MC3T3-E1 cells on titanium and zirconium was evaluated in this study. Mirror-polished titanium (Ti) and zirconium (Zr) disks and zirconium-sputter deposited titanium (Zr/Ti) were employed in this study. The surface of specimens were characterized using scanning electron microscopy and X-ray diffraction. Then, the cellular proliferation, differentiation and calcification of MC3T3-E1 cells on specimens were investigated. The surface of Zr/Ti was much smoother and cleaner than those of Ti and Zr. The proliferation of the cell was the same among three specimens, while the differentiation and calcification on Zr/Ti were faster than those on Ti and Zr. Therefore, Ti and Zr showed the identical hard tissue compatibility according to the evaluation with MC3T3-E1 cells. Sputter deposition may improve cytocompatibility.
|
| Volume |
34(5)
|
| Pages |
713-8
|
| Published |
2015-1-1
|
| DOI |
10.4012/dmj.2015-018
|
| PMID |
26438997
|
| MeSH |
3T3 Cells
Animals
Calcification, Physiologic / drug effects*
Cell Differentiation / drug effects
Mice
Osteogenesis / drug effects
Titanium / pharmacology*
Zirconium / pharmacology*
|
| IF |
1.359
|
| Resource |
| Human and Animal Cells |
MC3T3-E1(RCB1126) |
