Reference - Detail
| RRC ID | 61975 |
|---|---|
| Author | Hobro AJ, Kumagai Y, Akira S, Smith NI. |
| Title | Raman spectroscopy as a tool for label-free lymphocyte cell line discrimination. |
| Journal | Analyst |
| Abstract |
Unactivated lymphocytes are morphologically identical and biochemically relatively similar, making them difficult to distinguish from one another with conventional light microscopy. Here, we use Raman spectroscopy to provide biochemical information on the composition of different lymphocyte cell lines. As could be expected, the biochemical differences measured with Raman spectroscopy between lymphocyte cell lines are small, but in combination with partial least squares discriminant analysis it is possible not only to distinguish between T- and B-cells, but also between individual T-cell and B-cell lines. |
| Volume | 141(12) |
| Pages | 3756-64 |
| Published | 2016-6-21 |
| DOI | 10.1039/c6an00181e |
| PMID | 27067644 |
| MeSH | Cell Line Discriminant Analysis Humans Least-Squares Analysis Lymphocytes / cytology* Optical Imaging Spectrum Analysis, Raman* |
| IF | 3.978 |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Resource | |
| Human and Animal Cells | Jurkat |