Reference - Detail
| RRC ID | 62131 |
|---|---|
| Author | Ohsawa K, Watanabe Y, Sato H. |
| Title | Hantaan virus persistently infects marmoset B-lymphoblastoid cell line. |
| Journal | J Vet Med Sci |
| Abstract |
To investigate lymphoid cell Hantavirus (HV) interaction, we examined the replication of the HV strains, Hantaan 76-118 (HTN), SR-11, and B-1 with the B95a, LYM-1, CGM1, JM, Jurkat, MOLT-4, AT(L)5KY, BW5147, L1210, and Vero/E6 cells. HV-growth was determined by immunofluorescence and focus-forming assays. LYM-1 and Vero/E6 supported the growth of all HV strains, and B95a only HTN, while remaining cells did not sustain these strains. This is the first report to indicate the HV-replication in lymphoid cell lines. B95a and LYM-1 cells may be useful for revealing the mechanism of HV-infection in animals. |
| Volume | 57(5) |
| Pages | 931-4 |
| Published | 1995-10-1 |
| DOI | 10.1292/jvms.57.931 |
| PMID | 8593305 |
| MeSH | Animals B-Lymphocytes / pathology B-Lymphocytes / virology* Callithrix Cell Line Chlorocebus aethiops Fluorescent Antibody Technique Hantaan virus / classification Hantaan virus / isolation & purification Hantaan virus / physiology* Hemorrhagic Fever with Renal Syndrome / etiology Hemorrhagic Fever with Renal Syndrome / pathology Hemorrhagic Fever with Renal Syndrome / virology Humans Vero Cells Virus Replication / physiology |
| IF | 1.049 |
| Resource | |
| Human and Animal Cells | LYM-1(RCB0076) CGM1(RCB0566) Jurkat(RCB0806) |