Reference - Detail
| RRC ID | 62156 |
|---|---|
| Author | Hines ER, Collins JF, Ghishan FK. |
| Title | Molecular cloning of the murine PHEX gene promoter. |
| Journal | Biochim Biophys Acta |
| Abstract |
We report the novel cloning of the murine PHEX promoter, the gene that is mutated in X-linked hypophosphatemic rickets (XLH). Four promoter/reporter gene constructs, -133/+104, -542/+104, -1061/+104, and -2866/+104, showed significant luciferase activity (4.9-13.2-fold over background) when transfected into rat osteogenic sarcoma (UMR-106) cells. |
| Volume | 1493(3) |
| Pages | 333-6 |
| Published | 2000-10-2 |
| DOI | 10.1016/s0167-4781(00)00188-3 |
| PII | S0167-4781(00)00188-3 |
| PMID | 11018258 |
| MeSH | Animals Base Sequence Blotting, Northern Cloning, Molecular Gene Expression Regulation Luciferases / genetics Mice Molecular Sequence Data PHEX Phosphate Regulating Neutral Endopeptidase Polymerase Chain Reaction Promoter Regions, Genetic* Protein Biosynthesis Proteins / genetics* Rats Transcription, Genetic Tumor Cells, Cultured |
| IF | 3.411 |
| Resource | |
| Human and Animal Cells | MC3T3-E1(RCB1126) |