RRC ID 62186
Author Huang Y, Wang Y, Ning C, Nan K, Han Y.
Title Hydroxyapatite coatings produced on commercially pure titanium by micro-arc oxidation.
Journal Biomed Mater
Abstract A porous hydroxyapatite (HA) coating on commercially pure titanium was prepared by micro-arc oxidation (MAO) in electrolytic solution containing calcium acetate and beta-glycerol phosphate disodium salt pentahydrate (beta-GP). The thickness, phase, composition morphology and biocompatibility of the oxide coating were characterized by x-ray diffraction (XRD), electron probe microanalysis (EPMA), scanning electron microscopy (SEM) with an energy dispersive x-ray spectrometer (EDS) and cell culture. The thickness of the MAO film was about 20 microm, and the coating was porous and uneven without any apparent interface to the titanium substrates. The result of XRD showed that the porous coating was made up of HA film. The favorable osteoblast cell affinity gives HA film good biocompatibility. HA coatings are expected to have significant uses for medical applications such as dental implants and artificial bone joints.
Volume 2(3)
Pages 196-201
Published 2007-9-1
DOI 10.1088/1748-6041/2/3/005
PII S1748-6041(07)54321-4
PMID 18458472
MeSH 3T3 Cells Animals Bone Substitutes / chemistry* Cell Adhesion / physiology Cell Survival / physiology* Coated Materials, Biocompatible / chemistry* Durapatite / chemistry* Gases / chemistry Hot Temperature Materials Testing Mice Oxidation-Reduction Particle Size Surface Properties Titanium / chemistry*
IF 3.174
Resource
Human and Animal Cells MC3T3-E1(RCB1126)