論文 - 詳細
| RRC ID | 62705 |
|---|---|
| 著者 | Hirose R, Ikegaya H, Naito Y, Watanabe N, Yoshida T, Bandou R, Daidoji T, Itoh Y, Nakaya T. |
| タイトル | Survival of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and Influenza Virus on Human Skin: Importance of Hand Hygiene in Coronavirus Disease 2019 (COVID-19). |
| ジャーナル | Clin Infect Dis |
| Abstract |
BACKGROUND:The stability of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on human skin remains unknown, considering the hazards of viral exposure to humans. We generated a model that allows the safe reproduction of clinical studies on the application of pathogens to human skin and elucidated the stability of SARS-CoV-2 on the human skin. METHODS:We evaluated the stability of SARS-CoV-2 and influenza A virus (IAV), mixed with culture medium or upper respiratory mucus, on human skin surfaces and the dermal disinfection effectiveness of 80% (w/w) ethanol against SARS-CoV-2 and IAV. RESULTS:SARS-CoV-2 and IAV were inactivated more rapidly on skin surfaces than on other surfaces (stainless steel/glass/plastic); the survival time was significantly longer for SARS-CoV-2 than for IAV [9.04 h (95% confidence interval: 7.96-10.2 h) vs. 1.82 h (1.65-2.00 h)]. IAV on other surfaces was inactivated faster in mucus versus medium conditions, while SARS-CoV-2 showed similar stability in the mucus and medium; the survival time was significantly longer for SARS-CoV-2 than for IAV [11.09 h (10.22-12.00 h) vs. 1.69 h (1.57-1.81 h)]. Moreover, both SARS-CoV-2 and IAV in the mucus/medium on human skin were completely inactivated within 15 s by ethanol treatment. CONCLUSIONS:The 9-h survival of SARS-CoV-2 on human skin may increase the risk of contact transmission in comparison with IAV, thus accelerating the pandemic. Proper hand hygiene is important to prevent the spread of SARS-CoV-2 infections. |
| 巻・号 | 73(11) |
| ページ | e4329-e4335 |
| 公開日 | 2021-12-6 |
| DOI | 10.1093/cid/ciaa1517 |
| PII | 5917611 |
| PMID | 33009907 |
| PMC | PMC7665347 |
| MeSH | COVID-19* Hand Hygiene* Humans Influenza A virus* Orthomyxoviridae* SARS-CoV-2 |
| IF | 8.313 |
| リソース情報 | |
| ヒト・動物細胞 | MDCK(RCB0995) |