| RRC ID |
63643
|
| 著者 |
Yamanaka S, Matsui K, Fujimoto T, Takamura T, Saito Y, Matsumoto N, Tajiri S, Matsumoto K, Yokoo T.
|
| タイトル |
In vivo regeneration of neo-nephrons in rodents by renal progenitor cell transplantation.
|
| ジャーナル |
STAR Protoc
|
| Abstract |
Renal progenitor cells induced from pluripotent stem cells have attracted attention as a cell source for organ regeneration. Here, we report an in vivo protocol for the regeneration of urine-producing nephrons, i.e., neo-nephrons, in mice. We outline steps to transplant exogenous renal progenitor cells into the nephrogenic zone of transgenic mice and subsequently analyze these neo-nephrons. For complete details on the use and execution of this protocol, please refer to Fujimoto et al. (2020).
|
| 巻・号 |
2(1)
|
| ページ |
100314
|
| 公開日 |
2021-3-19
|
| DOI |
10.1016/j.xpro.2021.100314
|
| PII |
S2666-1667(21)00021-6
|
| PMID |
33554147
|
| PMC |
PMC7856474
|
| MeSH |
Animals
Cell Differentiation / physiology
Cell Separation / methods*
Humans
Kidney / cytology
Mice
Mice, Transgenic
Nephrons / growth & development*
Organogenesis / physiology
Pluripotent Stem Cells / physiology
Rats
Regeneration / physiology
Stem Cell Transplantation / methods*
Stem Cells / metabolism
|
| リソース情報 |
| ヒト・動物細胞 |
201B7(HPS0063) |
