Reference - Detail
| RRC ID | 64078 |
|---|---|
| Author | Aoyanagi T, Ikeya S, Kobayashi A, Kozaki A. |
| Title | Gene Regulation via the Combination of Transcription Factors in the INDETERMINATE DOMAIN and GRAS Families. |
| Journal | Genes (Basel) |
| Abstract |
INDETERMINATE DOMAIN (IDD) family proteins are plant-specific transcription factors. Some Arabidopsis IDD (AtIDD) proteins regulate the expression of SCARECROW (SCR) by interacting with GRAS family transcription factors SHORT-ROOT (SHR) and SCR, which are involved in root tissue formation. Some AtIDD proteins regulate genes involved in the synthesis (GA3ox1) or signaling (SCL3) of gibberellic acid (GA) by interacting with DELLA proteins, a subfamily of the GRAS family. We analyzed the DNA binding properties and protein-protein interactions of select AtIDD proteins. We also investigated the transcriptional activity of the combination of AtIDD and GRAS proteins (AtIDD proteins combined with SHR and SCR or with REPRESSOR of ga1-3 (RGA)) on the promoters of SCR,SCL3, and GA3ox1 by conducting a transient assay using Arabidopsis culture cells. Our results showed that the SCR promoter could be activated by the IDD and RGA complexes and that the SCL3 and GA3ox1 promoters could be activated by the IDD, SHR, and SCR complexes, indicating the possibility that these complexes regulate and consequently coordinate the expression of genes involved in GA synthesis (GA3ox1), GA signaling (SCL3), and root formation (SCR). |
| Volume | 11(6) |
| Published | 2020-6-2 |
| DOI | 10.3390/genes11060613 |
| PII | genes11060613 |
| PMID | 32498388 |
| PMC | PMC7349898 |
| MeSH | Arabidopsis / genetics* Arabidopsis / growth & development Arabidopsis Proteins / genetics* Co-Repressor Proteins / genetics* DNA-Binding Proteins / genetics Gibberellins / metabolism Mixed Function Oxygenases / genetics* Multigene Family / genetics Promoter Regions, Genetic / genetics Repressor Proteins / genetics Transcription Factors / genetics |
| IF | 3.759 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 2 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Arabidopsis / Cultured plant cells, genes | rpc00008 |