Reference - Detail
| RRC ID | 64527 |
|---|---|
| Author | Ötvös K, Miskolczi P, Marhavý P, Cruz-Ramírez A, Benková E, Robert S, Bakó L. |
| Title | Pickle Recruits Retinoblastoma Related 1 to Control Lateral Root Formation in Arabidopsis. |
| Journal | Int J Mol Sci |
| Abstract |
Lateral root (LR) formation is an example of a plant post-embryonic organogenesis event. LRs are issued from non-dividing cells entering consecutive steps of formative divisions, proliferation and elongation. The chromatin remodeling protein PICKLE (PKL) negatively regulates auxin-mediated LR formation through a mechanism that is not yet known. Here we show that PKL interacts with RETINOBLASTOMA-RELATED 1 (RBR1) to repress the LATERAL ORGAN BOUNDARIES-DOMAIN 16 (LBD16) promoter activity. Since LBD16 function is required for the formative division of LR founder cells, repression mediated by the PKL-RBR1 complex negatively regulates formative division and LR formation. Inhibition of LR formation by PKL-RBR1 is counteracted by auxin, indicating that, in addition to auxin-mediated transcriptional responses, the fine-tuned process of LR formation is also controlled at the chromatin level in an auxin-signaling dependent manner. |
| Volume | 22(8) |
| Published | 2021-4-8 |
| DOI | 10.3390/ijms22083862 |
| PII | ijms22083862 |
| PMID | 33917959 |
| PMC | PMC8068362 |
| MeSH | Arabidopsis / physiology* Arabidopsis Proteins / genetics* Arabidopsis Proteins / metabolism* Chromatin Assembly and Disassembly DNA Helicases / metabolism* Gene Expression Regulation, Plant Indoleacetic Acids / metabolism Organogenesis, Plant / genetics* Plant Development / genetics* Plant Roots / physiology* Promoter Regions, Genetic Protein Binding Signal Transduction |
| IF | 4.556 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 10 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Arabidopsis / Cultured plant cells, genes | pda20017 |