| RRC ID |
64545
|
| Author |
Crane RA, Cardénas Valdez M, Castaneda N, Jackson CL, Riley CJ, Mostafa I, Kong W, Chhajed S, Chen S, Brusslan JA.
|
| Title |
Negative Regulation of Age-Related Developmental Leaf Senescence by the IAOx Pathway, PEN1, and PEN3.
|
| Journal |
Front Plant Sci
|
| Abstract |
Early age-related developmental senescence was observed in Arabidopsis cyp79B2/cyp79B3 double mutants that cannot produce indole-3-acetaldoxime (IAOx), the precursor to indole glucosinolates (IGs), camalexin and auxin. The early senescence phenotype was not observed when senescence was induced by darkness. The cyp79B2/cyp79B3 mutants had lower auxin levels, but did not display auxin-deficient phenotypes. Camalexin biosynthesis mutants senesced normally; however, IG transport and exosome-related pen1/pen3 double mutants displayed early senescence. The early senescence in pen1/pen3 mutants depended on salicylic acid and was not observed in pen1 or pen3 single mutants. Quantitation of IGs showed reduced levels in cyp79B2/cyp79B3 mutants, but unchanged levels in pen1/pen3, even though both of these double mutants display early senescence. We discuss how these genetic data provide evidence that IAOx metabolites are playing a protective role in leaf senescence that is dependent on proper trafficking by PEN1 and PEN3, perhaps via the formation of exosomes.
|
| Volume |
10
|
| Pages |
1202
|
| Published |
2019-10-8
|
| DOI |
10.3389/fpls.2019.01202
|
| PMID |
31649689
|
| PMC |
PMC6792297
|
| IF |
4.402
|
| Resource |
| Arabidopsis / Cultured plant cells, genes |
pst04610
psh10821
psh19554 |
