論文 - 詳細
| RRC ID | 64610 |
|---|---|
| 著者 | Zhang X, Zong W, Hu Y, Luo N, Cheng W, Han X. |
| タイトル | A pH-responsive asymmetric lipid vesicle as drug carrier. |
| ジャーナル | J Microencapsul |
| Abstract |
In order to increase the loading efficiency of drug carriers, here we demonstrated a microfluidic method to fabricate an asymmetric vesicle, which contains trichloro(1H,1H,2H,2H-perfluoroocty-l)silane (TPS) inner leaflet and lipid outer leaflet. The asymmetric vesicle was characterised by fluorescence microscopy and Fourier transform infra-red spectrum. In vitro cytotoxicity of the vesicles carrying 5-fluorouacil (5-FU) has also been studied. |
| 巻・号 | 33(7) |
| ページ | 663-668 |
| 公開日 | 2016-11-1 |
| DOI | 10.1080/02652048.2016.1242668 |
| PMID | 27682414 |
| MeSH | Cell Line, Tumor Cytotoxins* / chemistry Cytotoxins* / pharmacokinetics Cytotoxins* / pharmacology Drug Carriers* / chemistry Drug Carriers* / pharmacokinetics Drug Carriers* / pharmacology Fluorouracil* / chemistry Fluorouracil* / pharmacokinetics Fluorouracil* / pharmacology Humans Hydrogen-Ion Concentration Lab-On-A-Chip Devices Lipids* / chemistry Lipids* / pharmacokinetics Lipids* / pharmacology Silanes / chemistry Silanes / pharmacokinetics Silanes / pharmacology |
| IF | 2.287 |
| リソース情報 | |
| ヒト・動物細胞 | OS-RC-2(RCB0735) |