RRC ID 64791
著者 Bloch S, Hagio H, Thomas M, Heuzé A, Hermel JM, Lasserre E, Colin I, Saka K, Affaticati P, Jenett A, Kawakami K, Yamamoto N, Yamamoto K.
タイトル Non-thalamic origin of zebrafish sensory nuclei implies convergent evolution of visual pathways in amniotes and teleosts.
ジャーナル Elife
Abstract Ascending visual projections similar to the mammalian thalamocortical pathway are found in a wide range of vertebrate species, but their homology is debated. To get better insights into their evolutionary origin, we examined the developmental origin of a thalamic-like sensory structure of teleosts, the preglomerular complex (PG), focusing on the visual projection neurons. Similarly to the tectofugal thalamic nuclei in amniotes, the lateral nucleus of PG receives tectal information and projects to the pallium. However, our cell lineage study in zebrafish reveals that the majority of PG cells are derived from the midbrain, unlike the amniote thalamus. We also demonstrate that the PG projection neurons develop gradually until late juvenile stages. Our data suggest that teleost PG, as a whole, is not homologous to the amniote thalamus. Thus, the thalamocortical-like projections evolved from a non-forebrain cell population, which indicates a surprising degree of variation in the vertebrate sensory systems.
巻・号 9
公開日 2020-9-8
DOI 10.7554/eLife.54945
PII 54945
PMID 32896272
PMC PMC7478893
MeSH Animals Biological Evolution* Cell Lineage* Embryo, Nonmammalian / embryology Thalamic Nuclei / embryology* Visual Pathways / embryology* Zebrafish / embryology*
IF 7.08
リソース情報
ゼブラフィッシュ gSAGFF279A, Tg(UAS:GFP)