RRC ID |
64959
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著者 |
Yoshido A, Šíchová J, Pospíšilová K, Nguyen P, Voleníková A, Šafář J, Provazník J, Vila R, Marec F.
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タイトル |
Evolution of multiple sex-chromosomes associated with dynamic genome reshuffling in Leptidea wood-white butterflies.
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ジャーナル |
Heredity (Edinb)
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Abstract |
Sex-chromosome systems tend to be highly conserved and knowledge about their evolution typically comes from macroevolutionary inference. Rapidly evolving complex sex-chromosome systems represent a rare opportunity to study the mechanisms of sex-chromosome evolution at unprecedented resolution. Three cryptic species of wood-white butterflies-Leptidea juvernica, L. sinapis and L. reali-have each a unique set of multiple sex-chromosomes with 3-4 W and 3-4 Z chromosomes. Using a transcriptome-based microarray for comparative genomic hybridisation (CGH) and a library of bacterial artificial chromosome (BAC) clones, both developed in L. juvernica, we identified Z-linked Leptidea orthologs of Bombyx mori genes and mapped them by fluorescence in situ hybridisation (FISH) with BAC probes on multiple Z chromosomes. In all three species, we determined synteny blocks of autosomal origin and reconstructed the evolution of multiple sex-chromosomes. In addition, we identified W homologues of Z-linked orthologs and characterised their molecular differentiation. Our results suggest that the multiple sex-chromosome system evolved in a common ancestor as a result of dynamic genome reshuffling through repeated rearrangements between the sex chromosomes and autosomes, including translocations, fusions and fissions. Thus, the initial formation of neo-sex chromosomes could not have played a role in reproductive isolation between these Leptidea species. However, the subsequent species-specific fissions of several neo-sex chromosomes could have contributed to their reproductive isolation. Then, significantly increased numbers of Z-linked genes and independent neo-W chromosome degeneration could accelerate the accumulation of genetic incompatibilities between populations and promote their divergence resulting in speciation.
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巻・号 |
125(3)
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ページ |
138-154
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公開日 |
2020-9-1
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DOI |
10.1038/s41437-020-0325-9
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PII |
10.1038/s41437-020-0325-9
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PMID |
32518391
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PMC |
PMC7426936
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MeSH |
Animals
Butterflies* / genetics
Evolution, Molecular*
Female
Sex Chromosomes*
Synteny*
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IF |
3.436
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リソース情報 |
カイコ |
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