RRC ID 65500
Author Tomoko Koda, Jun Takanari, Kentaro Kitadate, Hideki Imai
Title Enzyme-treated Asparagus Extract (ETAS) Enhances Memory in Normal Rats and Induces Neurite-outgrowth in PC12 Cells
Journal Natural Product Communications
Abstract Enzyme-treated asparagus extract (ETAS) contains various phytochemicals. It has been reported that ETAS protected early cognitive impairment of SAMP8 mice and Aβ-induced reduction of PC12 cell viability. In addition, ETAS had several functions on healthy people. The purpose of the present study was to investigate the effects of ETAS on normal memory function of rats and neurite-outgrowth of PC12 cells. ETAS significantly accelerated learning acquisition in in vivo and neurite-outgrowth in in vitro study. In conclusion, ETAS affected on memory function in early stage in normal rats. The basis of this effect may induce neurite-outgrowth in neurons.
Volume 12
Pages 1934578X1701201
Published 2017-10-1
DOI 10.1177/1934578x1701201027
IF 0.468
Resource
Human and Animal Cells PC-12(RCB0009)