Reference - Detail
| RRC ID | 66055 |
|---|---|
| Author | Li W, Huang C, Liu Q, Koike K. |
| Title | Bistinospinosides A and B, Dimeric Clerodane Diterpene Glycosides from Tinospora sagittata. |
| Journal | J Nat Prod |
| Abstract |
Two dimeric clerodane diterpene glycosides, namely, bistinospinosides A (1) and B (2), were isolated from the roots of Tinospora sagittata. Their structures were elucidated by extensive spectroscopic data interpretation. The compounds feature an unusual 1,4-epoxycyclohexane ring in their structures and may be biosynthetically constructed via an intermolecular Diels-Alder [4+2] cycloaddition from the corresponding clerodane diterpene. The compounds were evaluated in a nitric oxide inhibitory assay using J774.1 macrophage-like cells. |
| Volume | 80(9) |
| Pages | 2478-2483 |
| Published | 2017-9-22 |
| DOI | 10.1021/acs.jnatprod.7b00324 |
| PMID | 28836430 |
| MeSH | Diterpenes, Clerodane / chemistry Diterpenes, Clerodane / isolation & purification* Diterpenes, Clerodane / pharmacology* Glycosides / chemistry Glycosides / isolation & purification* Glycosides / pharmacology* Macrophages / chemistry Macrophages / drug effects* Molecular Structure Nitric Oxide / analysis* Nitric Oxide / chemistry Plant Roots / chemistry* Tinospora / chemistry* |
| IF | 3.782 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Blogs |
| Total number of mentions | 1 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | J774.1 |