RRC ID 6619
Author Li W, Bi X, Wang K, Li D, Satou T, Koike K.
Title Triterpenoid saponins from Impatiens siculifer.
Journal Phytochemistry
Abstract Triterpenoid saponins, impatienosides A-G, together with 12 known saponins, were isolated from the whole plants of Impatiens siculifer. Their structures were established on the basis of extensive 1D and 2D NMR and MS analyses coupled with chemical degradation. Cytotoxic activities of the isolated saponins were evaluated against three human cancer cell lines: human myeloid leukemia HL-60 cells, human stomach KATO-III adenocarcinoma, and human lung A549 adenocarcinoma.
Volume 70(6)
Pages 816-21
Published 2009-4-1
DOI 10.1016/j.phytochem.2009.03.022
PII S0031-9422(09)00136-8
PMID 19409580
MeSH Carbohydrate Sequence Cell Line, Tumor Drug Screening Assays, Antitumor Humans Impatiens / chemistry* Magnetic Resonance Spectroscopy Molecular Sequence Data Molecular Structure Saponins / chemistry* Saponins / pharmacology Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Infrared Triterpenes / chemistry* Triterpenes / pharmacology
IF 3.044
Times Cited 19
WOS Category PLANT SCIENCES BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Human and Animal Cells