Reference - Detail
| RRC ID | 66714 |
|---|---|
| Author | Munoz J, James K, Bottacini F, Van Sinderen D. |
| Title | Biochemical analysis of cross-feeding behaviour between two common gut commensals when cultivated on plant-derived arabinogalactan. |
| Journal | Microb Biotechnol |
| Abstract |
In this paper, we reveal and characterize cross-feeding behaviour between the common gut commensal Bacteroides cellulosilyticus (Baccell) and certain bifidobacterial strains, including Bifidobacterium breve UCC2003, when grown on a medium containing Larch Wood Arabinogalactan (LW-AG). We furthermore show that cross-feeding is dependent on the release of β-1,3-galacto-di/trisaccharides (β-1,3-GOS), and identified that the bga gene cluster of B. breve UCC2003 allows β-1,3-GOS metabolism. The product of bgaB is presumed to be responsible for the import of β-1,3-GOS, while the bgaA gene product, a glycoside hydrolase family 2 member, was shown to hydrolyse both β-1,3-galactobiose and β-1,3-galactotriose into galactose monomers. This study advances our understanding of strain-specific syntrophic interactions between two glycan degraders in the human gut in the presence of AG-type dietary polysaccharides. |
| Volume | 13(6) |
| Pages | 1733-1747 |
| Published | 2020-11-1 |
| DOI | 10.1111/1751-7915.13577 |
| PMID | 32385941 |
| PMC | PMC7533333 |
| MeSH | Bacteroides Bifidobacterium / genetics Feeding Behavior Galactans Gastrointestinal Microbiome* Humans |
| Altmetric score |
オルトメトリクス指標項目
|
| The most frequently cited source | X(Twitter) |
| Total number of mentions | 12 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM7017 |