論文 - 詳細
| RRC ID | 67807 |
|---|---|
| 著者 | Li B, Li J, An G, Zhao C, Wang C. |
| タイトル | Long-term and strong suppression against Microcystis growth and microcystin-release by luteolin continuous-release microsphere: Optimal construction, characterization, effects and proteomic mechanisms. |
| ジャーナル | Water Res |
| Abstract |
Microcystis-dominated cyanobacterial blooms (MCBs) severely threaten ecological health by causing hypoxia and releasing microcystins (MCs). Luteolin has potential as low-cost eco-safe algaecide against Microcystis, but to enhance sustainability of its algicidal effect and elucidate underlying mechanisms at proteomic level are urgently desirable. This study optimally constructed continuous-release microsphere (CRM) of luteolin with strong solidity and durability even after long-term immersion. Applying luteolin CRM, this study developed a long-term algicidal option to strongly inhibit Microcystis growth and MC-release until 49 days, with inhibition ratios of growth and MC-release (both ≥ 98%) and inhibitory effect-lasting time (nearly 50 days) of CRM superior to most former reports, and long-term strong inhibitory effects of CRM on Microcystis growth and MC-release kept stable at various nitrogen levels. Also, luteolin CRM rendered extracellular MCs content decrease to nearby acceptable threshold for drinking water. These signified a promising prospect of luteolin CRM in sustained effective control against toxigenic MCBs in waters of different eutrophic states. Comparative proteomic analysis showed that luteolin CRM significantly up-regulated photosynthesis and protein homestasis, but down-regulated other processes including stress response, MC-synthesis/release, glycolysis, amino acid synthesis, fatty acid synthesis/β-oxidation, tricarboxylic acid cycle, transcription, translation, transport, cell shaping and cell division. These implied that continuous stress of luteolin released from CRM induced Microcystis proteome towards a shift of higher energy storage but lower energy release/consumption, which largely disturbed its physiological metabolic processes and thus negatively impact its growth. Proteomics results shed newly deep insights on algicidal mechanisms of flavonoid in the form of CRM. |
| 巻・号 | 202 |
| ページ | 117448 |
| 公開日 | 2021-9-1 |
| DOI | 10.1016/j.watres.2021.117448 |
| PII | S0043-1354(21)00646-1 |
| PMID | 34364065 |
| MeSH | Luteolin Microcystins Microcystis* Microspheres Proteomics |
| IF | 9.13 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 4 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 藻類 | NIES-102 NIES-298 |