Reference - Detail
| RRC ID | 67809 |
|---|---|
| Author | Monteiro PR, do Amaral SC, Siqueira AS, Xavier LP, Santos AV. |
| Title | Anabaenopeptins: What We Know So Far. |
| Journal | Toxins (Basel) |
| Abstract |
Cyanobacteria are microorganisms with photosynthetic mechanisms capable of colonizing several distinct environments worldwide. They can produce a vast spectrum of bioactive compounds with different properties, resulting in an improved adaptative capacity. Their richness in secondary metabolites is related to their unique and diverse metabolic apparatus, such as Non-Ribosomal Peptide Synthetases (NRPSs). One important class of peptides produced by the non-ribosomal pathway is anabaenopeptins. These cyclic hexapeptides demonstrated inhibitory activity towards phosphatases and proteases, which could be related to their toxicity and adaptiveness against zooplankters and crustaceans. Thus, this review aims to identify key features related to anabaenopeptins, including the diversity of their structure, occurrence, the biosynthetic steps for their production, ecological roles, and biotechnological applications. |
| Volume | 13(8) |
| Published | 2021-7-27 |
| DOI | 10.3390/toxins13080522 |
| PII | toxins13080522 |
| PMID | 34437393 |
| PMC | PMC8402340 |
| MeSH | Animals Ecology Molecular Structure Peptides, Cyclic* / biosynthesis Peptides, Cyclic* / chemistry Peptides, Cyclic* / toxicity Protease Inhibitors / chemistry Protease Inhibitors / metabolism Protease Inhibitors / toxicity |
| IF | 3.531 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | News |
| Total number of mentions | 5 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Algae | NIES-81 NIES-204 NIES-595 |