論文 - 詳細
| RRC ID | 68146 |
|---|---|
| 著者 | Yu BS, Sung YJ, Choi HI, Sirohi R, Sim SJ. |
| タイトル | Concurrent enhancement of CO2 fixation and productivities of omega-3 fatty acids and astaxanthin in Haematococcus pluvialis culture via calcium-mediated homeoviscous adaptation and biomineralization. |
| ジャーナル | Bioresour Technol |
| Abstract |
Haematococcus pluvialis has attracted interest as a bio-platform for producing omega-3 fatty acids (ω-3 FA) and astaxanthin that have a great potential as anti-inflammatory drugs. This study aimed to concurrently enhance the CO2 fixation and the productivities of ω-3 FA and astaxanthin, which have been difficult to achieve because of the dissimilar culture methods for each goal, via calcium-mediated homeoviscous adaptation and biomineralization. As a result of 3 mM of Ca2+ addition, ω-3 FA content was improved by 31% due to Ca2+-induced homeoviscous adaptation. Biomineralization was promoted by the extracellular carbonic anhydrase, which resulted in 46.3% improvement in CO2 fixation. CaCO3 from the biomineralization was beneficially re-used in the H. pluvialis culture and triggered 178- and 522-fold increased biomass productivity and astaxanthin content, respectively, thanks to its anisotropic nature. The Ca2+-based productivity enhancement strategy was applied to large-scale culture which resulted improvement in overall bioprocess performance. |
| 巻・号 | 340 |
| ページ | 125720 |
| 公開日 | 2021-11-1 |
| DOI | 10.1016/j.biortech.2021.125720 |
| PII | S0960-8524(21)01061-0 |
| PMID | 34365300 |
| MeSH | Biomineralization Calcium Carbon Dioxide* Fatty Acids, Omega-3* Xanthophylls |
| IF | 7.539 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 1 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 3.0 |
| リソース情報 | |
| 藻類 | NIES-144 |